I love Strats, more than Gretsch for comfort, and unlike most, I do not have a tele. I have two Strats one is the Aerodyne with a very thin fast neck and modded with the first-gen hot noiseless pups. Great sounding pups and plenty of growl when I need it and a 60th Anniversary MIM Strat, it has Hot Tex Mex pups and is oh so southern blues, SRV like, in tone. the TexMex pups are singles all the way a bit closer to HB are the Noiseless which are noiseless HB style stacked pups than a bit closer to the HB side is the HS Filters in the Penguin, after that the full-on HB pups in the Minarick. A whole range of tones but with the Gretsch and the Minarick I can not do much more than change pups or pots etc. I had a bowed neck on a Strat and it was easily replaceable, the Thin Aerodyne neck is next to go because it actually is hurting my wrist, just too thin. I couldn't fix that easily on a Gretsch or set neck guitar. But as for tone if I want single, quack, clean chimey Strats can do it. If I want clean chimey clear Strats can do it. If I adjust my amp eq the tone, add a pedal, I can get quite a full and focused break up not a paf tone but close enough for me, and the 25.5" scale is my favorite. I wish my Penguin and Minarick had a 25.5" scale.