Audept becomes "The Guinea Pig"

Discussion in 'Fred's Barcalounge' started by audept, Dec 4, 2020.

  1. r0de0

    r0de0 Synchromatic

    622
    Jul 7, 2011
    Ontario, Canada
    Long live the Gold Dept.
     
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  2. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    Yes, it can be positively invigorating! :p
     
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  3. THE BALD REVEREND

    THE BALD REVEREND Electromatic

    74
    Jul 14, 2020
    MILAN - ITALY
    In Italy we say : " in bocca al lupo " , which is impossible to translate makin' sense but it could sound some like " **** the wolf ! " , SO ... **** THE WOLF , and thanks for becoming the Guinea pig , you deserve all the best !
     
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  4. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    Today I visited the clinical research center and was given yet another blood test and some information which must still remain confidential until public release. The results are extremely encouraging in my particular case and will likely be published in the next few months. While there were other participants in my trial, I have now volunteered for a singular experiment (just me alone) to take it to the next level (uncharted territory) My data will be used by the researchers to answer some further questions they have. I feel lucky and privileged to be useful in my later years. I hope to be able to share some of this with you after my confidentiality agreement expires. :cool::cool:
     
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  5. Ricochet

    Ricochet Senior Gretsch-Talker

    Nov 13, 2009
    Monkey Island
    Good luck Wyn...
     
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  6. drmilktruck

    drmilktruck I Bleed Orange

    May 17, 2009
    Plymouth, MN
    To go where no man has gone before! Will it help your guitar playing? :D

    seriously though, good luck, make us proud.
     
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  7. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    My guitar playing doesn't need medical research, it needs bonafide miracles of nature!
     
  8. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    Update for those who are still interested.
    I have completed the Phase 3 trial and the results are now in. The research doctors are very happy with the results and I have been "unblinded" from the trial and informed exactly what I was given and when. I had yet more blood tests for calibration purposes.
    I decided to go ahead with Phase 4 and receive another different drug early this week. There is no data on anyone who has done this, so it was a leap into the unknown. After discussing the risks with my docs they advised me that based on my previous test results it was very unlikely I would suffer any serious side effects. On Tuesday morning I got the Phase 4 dose and didn't feel a thing. I went to work and was fine all day, feeling smug in my apparent invulnerability. Well the docs were wrong! I woke up in the middle of the night and instantly realized I was in trouble. Intense pain in my shoulder and almost couldn't move my arm. Fever, alternate chills and sweating, high temperature, stomach cramps, bad headaches and feeling really ill. I called the docs and they were surprised I had such a bad reaction but advised me it would pass. I spent 3 days in bed and dropped 3 Kgs through dehydration. I finally recovered last night and now today I'm feeling pretty normal for a 73 yr old with too many bad habits. I had a brief time to consider the wisdom of what I was doing and I have decided to go ahead with Phase 5 in 12 weeks time. This will be another dose of the 2nd drug which will put me in very rare territory indeed, nobody else has been in this situation, but the data from the blood plasma test results will be invaluable.
    Just to complicate matters in 3 weeks I will receive a new and stronger version of the Flu vaccine intended for people over 70. The docs say it shouldn't skew the other test results.
    The big test will come with the Phase 5 dose, I'm kinda apprehensive about it but still determined to go ahead.
    I'm now operating on the premise that what doesn't kill you, makes you stronger.
     
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  9. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    Update: 10 days since I had the extra strength flu vaccine. I had a mild reaction, felt like crap for a day, then recovered totally. Now only 5 weeks to Phase 5 and a leap into uncharted territory.
     
  10. capnhiho

    capnhiho Country Gent

    Feb 16, 2013
    California
    It sounds like you’ve evolved from Guinea Pig to Energizer Bunny….!
     
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  11. Bertotti

    Bertotti Friend of Fred

    Jul 20, 2017
    South Dakota
    In the Marines they asked for volunteers one day to go to the hanger and get the new experimental flu shot. So naturally, I got voluntold. VAccine for 1000 but a mishap put it in the first 100. All but two people got the flu by the end of the day and were out for two to three weeks. I was one who didn't get sick but everyone I came in contact with, in my shop got sick. I have not had the flu since. 35 years now and counting. Got the second shingles sot yesterday, the first was ruff and this was just as bad.

    I applaud your desire to be the guinea pig but there are risks, so good luck!
     
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  12. radd

    radd Country Gent

    Dec 27, 2017
    Santa Cruz
    It sounds very encouraging, that is wonderful.

    Good for you for agreeing to be a “lab mouse”.

    Please keep us informed and keep playing music....
     
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  13. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    OK another update: I had the Phase 5 dose 2 days ago. I had a rough 24 hours with some side effects again but this time only about 30% as intense as the last time. I was fully back to normal today, so everything is good. I had been asking my docs to seek approval from the medical authorities to let me have another 2 doses of a 3rd different type of drug, but I have been advised that is unlikely to be allowed. While they say the blood plasma data would be very interesting, it would be of limited use since I would be the only recipient and any results would only relate to myself. I'm still determined to push the boundaries as far as possible so I have gone back to the Phase 1 & 2 trial drug company and volunteered to be the first to get their upcoming booster dose which is still in development at this stage. I have formed a good relationship with the Professor leading the clinical research team and I have a good chance of being involved. It will be at least 6 months before this is possible, so in the meantime I have scheduled a cardio stress echo test, more skin cancer scans, a thyroid fine needle biopsy (painful! :() and 12 month checkup for my paratoidectomy! My final blood tests are scheduled for August 27. I'm so happy to be contributing to medical research and still being useful and relevant at my age!
     
    Last edited: Jul 22, 2021
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  14. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
  15. drmilktruck

    drmilktruck I Bleed Orange

    May 17, 2009
    Plymouth, MN
    Thank you for doing that, audept!
     
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  16. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    Final update:
    Today was day #337 and the final day of the trial. I gave more blood for the final analysis and data update. I had a meeting with the chief research doctor and a final debrief. The results have been very helpful and will contribute to further developments. In my case there has been a surprising small but measurable change in 2 of my underlying chronic conditions. I have authorized all my specialists to cooperate together to decide whether these changes are a coincidence or an unexpected bonus.
    During the final meeting I was told that they have a significant new drug under development and will be starting trials early 2022. Of course I requested to be signed up immediately and was pre-approved for the new trial!
     
  17. Synchro

    Synchro The artist formerly known as: Synchro Staff Member

    Jun 2, 2008
    Tucson
    Admin Post
    After all of those blood tests, they might come back and say that you are in perfect health, except for a lowered blood count. :)
     
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  18. audept

    audept Senior Gretsch-Talker

    Age:
    74
    Dec 1, 2010
    Sydney, Australia
    I'm thinking my lowered blood pressure is because of the constant blood tests!
    ;)
     
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  19. Synchro

    Synchro The artist formerly known as: Synchro Staff Member

    Jun 2, 2008
    Tucson
    Admin Post
    Could be.
     
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  20. Bertotti

    Bertotti Friend of Fred

    Jul 20, 2017
    South Dakota
    Maybe they had it right in medieval times, leeches for bloodletting. You could do that at home! o_O
     
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